4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:原厂直采,平行进口,授权代理(蚂蚁淘为您服务)
咨询热线电话
4000-520-616
当前位置: 首页 > 新闻动态 >
新闻详情
BMS 754807 |cas 1001350-96-4, |DC Chemicals|Supplier|Price|Buy...
来自 : 新浪博客 发布时间:2021-03-25
Chemicals|Supplier|Price|Buy
DCChemicalsSupply:BMS 754807,cas1001350-96-4,, Cat No. DC3126, In stockContact: website:www.dcchemicals.com,sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,Tel: +86-21-61454686;Fax:+86-21-61642636;Product name: BMS754807, Synonym: BMS-754807,BMS 754807, Cat No. DC3126, Cas:1001350-96-4,, ChemicalName:(S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide,Molecular Formula: C23H24FN9O, MW: 461.49BMS754807 Cas#1001350-96-4,.Purity: 98%.Best Price andQuality in the Market!Supplied by DC Chemicals! BMS-754807 is apotent and reversible inhibitor of IGF-1R/IR family kinases,inhibits IGF-1R, IR, Met, TrkA and TrkB with IC50 of 1.8 nM, 1.7nM, 5.6 nM, 7.4 nM and 4.1 nM, respectively.BMS-754807 is an orally bioavailable antagonist of humaninsulin-like growth factor type I receptor (IGF-1R) with potentialantineoplastic activity. IGF-1R antagonist BMS-7548077 binds toIGF-1R, preventing IGF-1 ligand binding and activation ofIGF-1R-mediated signaling pathways; inhibition of IGF-1R-mediatedsignaling pathways may result in the inhibition of tumor cellproliferation and the induction of tumor cell apoptosis. IGF-1R isa receptor tyrosine kinase expressed on most tumor cells and isinvolved in mitogenesis, angiogenesis, and tumor cell survival.Check for active clinical trials or closed clinical trials usingthis agent. (NCI Thesaurus)For the detailed information about the solubility of BMS754807 in water, the solubility of BMS 754807 in DMSO, thesolubility of BMS 754807 in PBS buffer, the animal experiment ofBMS 754807,the in vivo and in vitro test of BMS 754807,the cellexperiment of BMS 754807,the IC50 and EC50 of BMS 754807pleasecontact DC Chemicals.

本文链接: http://bmschemicals.immuno-online.com/view-777377.html

发布于 : 2021-03-25 阅读(0)
品牌分类
其他
联络我们
服务热线:4000-520-616
(限工作日9:00-18:00)
QQ :1570468124
手机:18915418616
官网:http://