BMS-599626 (AC480) |cas 714971-09-2 |DC Chemicals|Supplier|Price|Bu...

来自 : 新浪博客 发布时间：2021-03-25

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DCChemicalsSupply:BMS-599626 (AC480),cas714971-09-2, Cat No. DC3105, In stockContact: website:www.dcchemicals.com,sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,Tel: +86-21-61454686;Fax:+86-21-61642619；Product name: BMS-599626 (AC480), Synonym: BMS599626,AC-480, BMS 599626 (AC480), Cat No.DC3105, Cas: 714971-09-2, Chemical Name:(S)-morpholin-3-ylmethyl4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-ylcarbamate,Molecular Formula: C27H27FN8O3.HCl, MW: 567.01BMS-599626 (AC480) Cas#714971-09-2.Purity: 98%.Best Priceand Quality in the Market!Supplied by DC Chemicals! BMS-599626(AC480) is a selective and efficacious inhibitor of HER1 and HER2with IC50 of 20 nM and 30 nM, respectively.BMS-599626 is an orally bioavailable inhibitor of the HER1,HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM,respectively) with potential antineoplastic activity. BMS-599626inhibits human epidermal growth factor receptors (HER) HER1, HER2and HER4, thereby inhibiting the proliferation of tumor cells thatoverexpress these receptors. Check for active clinical trials orclosed clinical trials using this agent. (NCI Thesaurus).For the detailed information about the solubility ofBMS-599626 (AC480) in water, the solubility of BMS-599626 (AC480)in DMSO, the solubility of BMS-599626 (AC480) in PBS buffer, theanimal experiment of BMS-599626 (AC480),the in vivo and in vitrotest of BMS-599626 (AC480),the cell experiment of BMS-599626(AC480),the IC50 and EC50 of BMS-599626 (AC480)please contact DCChemicals.